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The latest number of COVID-19 cases with mutations consistent with B.1.1.529 in England are published on UKHSAs social media channels. More investigation is required to fully determine the extent of these mutations impact. The individuals that have tested positive are not connected to each other and are not linked to the previously confirmed cases. An important question is whether BA.2 or BA.3 will become a new dominating "variant of concern". Nine cases have also been identified in Scotland, with 5 cases in the Lanarkshire area and 4 in the Greater Glasgow and Clyde area. What are the most common symptoms of Omicron BA.2? Over 40% of hospital admissions were in London. However, any stay in hospital for a child is too long if youre a parent and its important we all take precautions to avoid the spread of infection. BA.2.75.2 as a new variant but singled it out as an . Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, National flu and COVID-19 surveillance report, higher risk of becoming seriously ill from respiratory infections, including COVID-19, this data should be interpreted with caution, This assessment is based on analysis of UK data, data on Omicron cases is published regularly here, Six cases of the SARS-CoV-2 variant known as B.1.1.529, Investigation of SARS-CoV-2 variants of concern: variant risk assessments, Investigation of SARS-CoV-2 variants: technical briefings, Coronavirus (COVID-19): guidance for local government, let fresh air in if meeting others indoors, wear a face covering or a face mask, particularly if you are in crowded and enclosed spaces. There is no data to suggest that BA.2 leads to more severe disease than previous Omicron sub-variants. Our exceptional vaccine rollout means the number of people severely affected by COVID-19 is low, and the UKs innovation and research has discovered life-saving treatments for those most at risk from COVID-19. Based on the reports from doctors treating the Covid variant and patients battling. One individual diagnosed in hospital has sadly died. BA.2 omicron symptoms According to the CDC, the symptoms of Covid-19, including BA.2, are: Fever or chills Cough Shortness of breath or difficulty breathing Fatigue Muscle or body. The most affected local authorities are West Northamptonshire, where there are 49 confirmed cases and 68 SGTF, and Manchester, where there are 7 confirmed cases and 61 SGTF. Francois Balloux, Professor of Computational Systems Biology and director of the UCL Genetics Institute, said that BA.1 and BA.2 "can be considered as two epidemiologically largely equivalent sub-lineages of Omicron". A BA2 variant's symptoms are similar to those of Omicron. The UKHSAs COVID-19 variant technical briefing 43, published today, includes epidemiological analysis that shows that Omicron BA.4 and BA.5 now make up more than half of new COVID-19 cases in England, accounting for approximately 22% and 39% of cases, respectively. The UK Health Security Agency (UKHSA) has released a new variant technical briefing detailing updated analysis of epidemiological and genomic data relating to SARS-CoV-2 variants currently circulating in the UK, including the XBB.1.5 variant which has been increasing in the US in recent months. UKHSA analysis shows that the risk of hospital admission for an identified case with Omicron is reduced compared to a case of Delta. There are also hybrid strains, such as XE, which is a combination of BA.1 and BA.2 By Alex Finnis The total number of confirmed cases in England is now 13. Neither have currently been designated as variants of concern. A booster dose was associated with a 74% reduced risk of hospitalisation in the first 2 to 4 weeks after vaccination, with the figure dropping to 66% 10 weeks or more after this dose. Trends in SGTF over and time are however affected by the coverage of laboratories contributing to this surveillance data. Data on this wont be available for several weeks. As the coronavirus continues to evolve, a new highly contagious Omicron variant is appearing in India and other nations, including the United States, experts say.. B.1.1.529 has a large number of mutations in the gene coding for the spike protein, and also in other parts of the viral genome. There is further data showing that effectiveness against symptomatic disease is significantly lower compared to the Delta variant, and wanes more quickly. March 31, 2022. A study of 8,500 households and 18,000 individuals conducted by Denmark's SSI found that BA.2 was "substantially" more transmissible than BA.1. Follow the latest self-isolation rules if you develop symptoms wear a mask where required to do so, take regular LFD tests and observe good hand hygiene. It is vital that everyone over the age of 40 who is eligible for a booster jab comes forward as soon as possible to get increased protection against this new variant. Any variants showing evidence of spread are rapidly assessed. The study also showed evidence to suggest that the BA.2 sub-variant is better able to evade vaccines. These include a high temperature, a new. The individual tested positive after travel to the UK and is linked to travel to Southern Africa. This analysis is preliminary and highly uncertain because of the small numbers of Omicron cases currently in hospital, inability to effectively measure all previous infections and the limited spread of Omicron into older age groups. It is testament to the diligence and scientific expertise of my colleagues at UKHSA, and the genomic sequencing capacity developed through the pandemic, that this new variant has been identified and analysed so quickly. Thats why its critical that anyone with COVID-19 symptoms isolates and gets a PCR test immediately. "Looking at other countries where BA.2 is now overtaking, we're not seeing any higher bumps in hospitalisation than expected," the WHO's Dr Boris Pavlin says. Genomes have now been uploaded from South Africa, Botswana and Hong Kong but the extent of spread is not yet determined. The UK Health Security Agency (UKHSA) has identified 2 further cases of COVID-19 with mutations consistent with B.1.1.529 in England, in addition to the previous 3 confirmed cases of the SARS-CoV-2 variant known as B.1.1.529 on 27 and 28 November. Dr Meera Chand, Director of Clinical and Emerging Infections at UKHSA, said: The reclassification of these variants as variants of concern reflects emerging evidence on the growth of BA.4 and BA.5 internationally and in the UK. AstraZeneca was the main vaccine used early in the programme in care homes and among those in clinical risk groups. Those aged 18 to 39 should wait to be called. Top of the list with a prevalence of 80. We will continue to monitor this situation closely and recommend appropriate public health measures if needed. The breakdown of cases by local authority is: The UK Health Security Agency (UKHSA) has identified 9 further cases of coronavirus (COVID-19) with mutations consistent with B.1.1.529 in England, in addition to the previous 13 confirmed cases of the SARS-CoV-2 variant known as B.1.1.529. The designation was made on the basis of increasing numbers of BA.2 sequences identified both domestically and internationally. These are some of the symptoms that you should be looking out for: High temperature. Case rates remain high throughout the UK and we must remain vigilant and take up vaccinations. These people are spread around the country and are a mix of age ranges between 18 to 85 years the majority had received 2 doses of vaccination. Omicron has a deletion atposition69/70of the spike proteinwhich allows it to be tracked through S gene target failure(SGTF)in some PCR tests. As part of UKHSAs routine genomic surveillance, approximately 15 to 20% of all positive PCR tests are also sent for sequencing. The symptoms of omicron BA.2.75 are mostly flu-like and may last more than 4-5 days. The omicron variant of the coronavirus was first detected in late 2021. I urge you to come forward as soon as youre eligible to help keep yourself and your loved ones safe. Work is underway to identify any links to travel. 1. Please come forward to receive your booster as soon as possible. #India is another country where #SARS_CoV_2 BA.2 is rapidly replacing #Delta & #Omicron BA.1. The early observations for 2 doses of AstraZeneca are particularly likely to be unreliable as they are based on small numbers and are likely to reflect an older population and a population with more co-morbidities than those given the Pfizer vaccine. We will continue to closely analyse all available biological, epidemiological and genomic evidence for any SARS-CoV-2 variant in the UK or internationally. While signs remain encouraging on Omicrons severity compared with Delta, the high levels of community transmission continue and may cause pressures on health services. While BA.2 appears to be more transmissible than previous variants, there is no data yet to suggest that it is any more severe. Following the first 2 confirmed cases of the SARS-CoV-2 variant known as B.1.1.529 on 27 November, the UK Health Security Agency (UKHSA) has identified one further case of COVID-19 with mutations consistent with B.1.1.529 in the UK. Studies in the UK reveal (where stealth Omicron is already spreading at a high rate) that people infected with the sub-variant show gut-related . "We must remain vigilant and take up vaccinations. As previously published, data continues to show vaccine effectiveness against hospitalisation for Omicron remains high. The proportion of test results displaying SGTF has been very low in recent months but an increase has been observed in the past week. These changes will take effect as of 1 April 2022 and will be reflected in full in future technical briefings. Those are pretty similar to what people experience with a cold or other seasonal viruses. People suffering From the Omicron BA2 variant said they had fever and body Aches. As we all work to limit the high levels of transmission of this variant over the Christmas period, we are urging people to test regularly, particularly before attending social gatherings. The first genomes of this variant were uploaded to the international GISAID database on 22 November. UKHSA is monitoring the situation closely, in partnership with scientific and public health organisations across the world. This paper can be found as a pre-print, and the data is referred to in the latest vaccine surveillance report. Early analyses suggest an increased growth rate compared to BA.1, however, growth rates have a low level of certainty early in the emergence of a variant and further analysis is needed. New sub-lineages within Delta continue to be identified. Vaccine efficacy analysis continues to show lower effectiveness for symptomatic Omicron disease. UKHSA has performed an initial laboratory evaluation of the current lateral flow devices (LFDs) for COVID-19 in current use in the UK. Our findings suggest the current wave of Omicron infections is unlikely to lead to a major surge in severe disease in care home populations with high levels of vaccine coverage and/or natural immunity. A thirddose was associated with a 68% (95% confidence interval 52 to 82%) reduced risk of hospitalisation when compared to similar unvaccinated individuals. By the summer of 2022, the BA.5 variant was the most dominant strain in the US. As is routine for any new variants under investigation,UKHSAis carrying out laboratory and epidemiological investigations to better understand the characteristics of this variant. Work is underway to identify any links to travel to Southern Africa. UKHSAis carrying out targeted testing at locations where the positive cases were likely to be infectious. These groups have been prioritised for booster doses since the start of the rollout in September to increase their protection. UKHSA has also released a variant risk assessment for Omicron BA.4 and BA.5, summarising the emerging epidemiology and laboratory evidence. Dr Jenny Harries, Chief Executive ofUKHSA, said: We are continuing our efforts to understand the effect of this variant on transmissibility, severe disease, mortality, antibody response and vaccine efficacy. Susan Hopkins, Chief Medical Advisor at UKHSA, said: This latest set of analysis once again demonstrates that a booster dose of the vaccine provides you with significant protection against hospitalisation from Omicron. Two-thirds with Omicron say they had Covid before. UK Health Security Agency (UKHSA) has published variant technical briefing 24. Vaccination remains our best defence against future COVID-19 waves, so it is still as important as ever that people come take up all the doses for which they are eligible as soon as possible. Getting your booster jab remains the most effective way of protecting yourself and others from infection and severe disease. So far, there is insufficient evidence to determine whether BA.2 causes more severe illness than Omicron BA.1, but data is limited and UKHSA continues to investigate. A detrimental change in biological properties (changes in transmissibility, severity or immune evasion) compared to the current dominant variant. Vaccination is critical to help us bolster our defences against this new variant please get your first, second or booster jab without delay. It has since swept the globe, eventually vanquishing other variants including delta. So, like the original omicron strain (BA.1), the primary symptoms of a mild BA.2 infection are a cough, fever, fatigue and possible loss of taste or smell. 1 case has been identified in Wales. Data continues to show COVID-19 poses a very low health risk to children and infants. The latest version raising alarms is an emerging subvariant of Omicron called BA.2. Recent studies suggest that BA.2 has a. However, increases in SGTF can give a useful early indication of variant spread. Thanks to very high levels of vaccine coverage we already have a robust wall of defence against COVID-19 as new variants emerge. The increasing prevalence of Omicron BA.4 and BA.5 is likely to be a factor in the recent increase in cases seen in the UK and elsewhere, though there is currently no evidence that Omicron BA.4 and BA.5 cause more severe illness than previous variants. It is also absolutely critical that we all do what we can to reduce transmission in the community so that we have time to administer as many booster doses as possible. A recombinant variant occurs when an individual becomes infected with 2 or more variants at the same time, resulting in a mixing of their genetic material within the patients body. Updated Jan. 27, 2023 The omicron subvariant of COVID-19, BA.5, became one of the dominant strains of the virus in the fall of 2022 in the U.S. At that time, it was the most easily spread strain to date and is able to evade immunity from COVID infection and vaccination. The BA.2 subvariant of Omicron, or the "stealth" variant, has been outcompeting the previously dominant BA.1 subvariant in several countries. Health and Social Care Secretary Sajid Javid said: This data is yet more evidence that vaccines remain our best line of defence against COVID-19. As of May 2022, BA.2.12.1 was spreading in the US and two new subvariants of Omicron named BA.4 and BA.5, first detected in January 2022, spread in South Africa. So far, there have been 717 V-22OCT-01 sequences uploaded from the UK to the international GISAID database. After 2 doses, vaccine effectiveness was 9% and 13% respectively for BA.1 and BA.2, after 25+ weeks. The variant technical briefing also includes updated analysis on Omicron BA.2, currently the dominant variant in the UK. Anyone who is contacted because of a link to a probable or possible Omicron case will be asked to take a PCR test, even if they have received a positive COVID-19PCRtestwithin the last 90 days. The World Health Organization has been monitoring SARS-CoV-2 (the virus that causes Covid-19) since January 2020, during which time the variant Omicron has been identified, which is technically known as BA.1 or B.1.1.529.The WHO is now monitoring a sub-variant of Omicron, known as BA.2, which has been described as "stealth Omicron," because it has genetic mutations that potentially make it . A booster dose for everyone over 18 years is now recommended and will be available at a minimum of 3 months from your last primary course jab. The individuals that have tested positive and their contacts are all isolating. Teams nationally and locally are working at pace to identify and trace all close contacts of every Omicron case. There is currently no evidence of community transmission within the UK. Work from home if you are able to, wear a mask indoors around other people, and ventilate indoor spaces well. We have started to see cases where there are no links to travel, suggesting that we have a small amount of community transmission. As of 20 October, there were 15,120 cases of VUI-21OCT-01 confirmed by whole genome sequences in England since it was first detected in July. UKHSA continues to monitor and study variants of SARS-CoV-2 closely and is working with academic partners to rapidly assess the significance of the lineages BA.4 and BA.5. Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. These are potentially biologically significant mutations which may change the behaviour of the virus with regards to vaccines, treatments and transmissibility. Technical Briefing 34 contains further analysis on symptom comparison on Omicron and Delta. Therefore, although early suggestions are that individuals may be less likely to require hospitalisation, many more people are likely to become infected. As viruses mutate into new variants, they sometimes split or branch off into sub-lineages.

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